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Cinematic 3D visualization of the human heart and vascular network with illuminated circulation.
Category

Heart & Circulation

Cardiac, vascular, circulation, and blood-flow pathways under study.

  • 10 research profiles
  • 9 peptides + 1 blends
  • Evidence review in progress

10 results

  • Alprostadil

    Other research compound

    Researchers are studying this compound in relation to vascular tone and circulation pathways.

    • Heart & Circulation

    Evidence level

    Level 5 · Regulatory Review or Established Clinical Use

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Approved prostaglandin therapy in urology and neonatal care.

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  • ARA-290

    Individual peptide

    ARA-290 is examined in studies of cardiac and microvascular pathways.

    • Heart & Circulation
    • Muscle & Recovery
    • Immune & Inflammation
    • +1 more

    Evidence level

    Level 4 · Controlled Human Studies

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Randomized controlled trials in neuropathic pain and sarcoidosis.

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  • Cardiogen

    Individual peptide

    Research interest in Cardiogen centres on endothelial function and blood-flow signaling.

    • Heart & Circulation
    • Healthy Aging & Longevity

    Evidence level

    Level 2 · Animal Research

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Animal and cell bioregulator studies from a limited research group.

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  • EPO

    Other research compound

    This compound is examined in studies of cardiac and microvascular pathways.

    • Heart & Circulation

    Evidence level

    Level 5 · Regulatory Review or Established Clinical Use

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Approved erythropoiesis-stimulating agent in clinical use.

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  • Humanin

    Individual peptide

    Research interest in Humanin centres on endothelial function and blood-flow signaling.

    • Heart & Circulation
    • Cellular Energy
    • Healthy Aging & Longevity

    Evidence level

    Level 2 · Animal Research

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Animal and cell studies of mitochondrial and neuroprotective signaling.

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  • MOTS-c

    Individual peptide

    MOTS-c is examined in studies of cardiac and microvascular pathways.

    • Heart & Circulation
    • Metabolism & Weight
    • Muscle & Recovery
    • +2 more

    Evidence level

    Level 2 · Animal Research

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Animal and cell studies of mitochondrial signaling; human data minimal.

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  • SS-31

    Individual peptide

    Research interest in SS-31 centres on endothelial function and blood-flow signaling.

    • Heart & Circulation
    • Muscle & Recovery
    • Cellular Energy
    • +2 more

    Evidence level

    Level 4 · Controlled Human Studies

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Randomized elamipretide trials in mitochondrial and cardiac disease.

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  • SS-31 + MOTS-c

    Blend · 2 components

    Research interest in this blend centres on endothelial function and blood-flow signaling.

    • Heart & Circulation
    • Metabolism & Weight
    • + 4 more

    Published evidence — exact blend

    Not yet reviewed

    Components (reviewed separately)

    • SS-31L4
    • MOTS-cL2
    Explore blend →
  • Vesugen

    Individual peptide

    Vesugen is examined in studies of cardiac and microvascular pathways.

    • Heart & Circulation
    • Healthy Aging & Longevity

    Evidence level

    Level 1 · Laboratory Research

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Laboratory bioregulator work only.

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  • VIP

    Individual peptide

    Research interest in VIP centres on endothelial function and blood-flow signaling.

    • Heart & Circulation
    • Brain & Cognition
    • Gut & Digestion
    • +1 more

    Evidence level

    Level 4 · Controlled Human Studies

    Claim: Vascular function and circulation

    1 Laboratory2 Animal3 Early Human4 Controlled Human5 Established

    Controlled aviptadil trials in respiratory and pulmonary conditions.

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How evidence levels work

How to read the evidence

Every result card shows the same five-segment bar. Each level below matches the color of that segment.

  1. Level 1: Laboratory Research

    Observed in cells, tissue, or computational models only.

  2. Level 2: Animal Research

    Studied in animal models; results often do not transfer to people.

  3. Level 3: Early Human Research

    Human research

    Small, early-stage, or uncontrolled studies in humans.

  4. Level 4: Controlled Human Studies

    Human research

    Randomized or otherwise controlled human trials exist.

  5. Level 5: Regulatory Review or Established Clinical Use

    Human research

    Reviewed by a regulator or established in clinical practice for a specific use.

Evidence is rated by claim—not popularity. More studies do not always mean stronger evidence.

A higher level describes research maturity. It is not a recommendation or endorsement.

Educational information only. Not medical advice.

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